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References

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References

References

131l-omburtamab radioimmunotherapy for neuroblastoma central nervous system/leptomeningeal metastases. Clinicaltrials.gov website (U.S. National Library of Medicine). https://clinicaltrials.gov/ct2/show/NCT03275402. Last updated March 11, 2019. Accessed May 29, 2019.

About DIPG. DIPG Registry website. https://dipgregistry.org/patients-families/about-dipg/. Accessed November 13, 2018.

Agarwal A, Ressler D, Snyder G. The current and future state of companion diagnostics. Pharmgenomics Pers Med. 2015;8:99-110. doi: 10.2147/PGPM.S49493.

Ahmed M, Cheng M, Cheung IY, Cheung N-K. Human derived dimerization tag enhances tumor killing potency of a T-cell engaging bispecific antibody. Oncoimmunology. 2015;4(4):e989776-1-e989776-11. doi: 10.4161/2162402X.2014.989776.

Ahmed M, Cheng M, Zhao Q, et al. Humanized affinity-matured monoclonal antibody 8H9 has potent antitumor activity and binds to FG loop of tumor antigen B7-H3. J Biol Chem. 2015;290(50):30018-30029.
doi: 10.1074/jbc.M115.679852.

Ahmed M, Hu J, Cheung N-K. Structure based refinement of a humanized monoclonal antibody that targets tumor antigen disialoganglioside GD2. Front Immunol. 2014;5:372. doi:  10.3389/fimmu.2014.00372.

American Cancer Society website. https://cancer.org. Accessed May 29, 2019.

Brain tumor. Mayo Clinic website. https://www.mayoclinic.org/diseases-conditions/brain-tumor/symptoms-causes/syc-20350084. Accessed May 29, 2019.

Cheal SM, Xu H, Guo HF, Zanzonico PB, Larson SM, Cheung N-K. Preclinical evaluation of multistep targeting of diasialoganglioside GD2 using a IgG-scFv bispecific antibody with high affinity for GD2 and DOTA metal complex. Mol Cancer Ther. 2014;13(7):1803-1812. doi: 10.1158/1535-7163.MCT-13-0933.

Cheng M, Ahmed M, Xu H, Cheung N-K. Structural design of disialoganglioside GD2 and CD3-bispecific antibodies to redirect T cells for tumor therapy. Int J Cancer. 2015;136(2):476-486. doi: 10.1002/ijc.29007.

Cheung N-K, Ostrovnaya I, Kuk D, Cheung IY. Bone marrow minimal residual disease was an early response marker and a consistent independent predictor of survival after anti-GD2 immunotherapy. J Clin Oncol. 2015;33(7):755-763. doi: 10.1200/JCO.2014.57.6777.

Companion diagnostics. U.S. Food and Drug Administration website. https://www.fda.gov/medical-devices/vitro-diagnostics/companion-diagnostics. Accessed February 8, 2019.

Corbin ZA, Nagpal S. Leptomeningeal metastases. JAMA Network website. https://jamanetwork.com/journals/jamaoncology/fullarticle/2513899. Accessed July 1, 2019.

Davidoff AM. Neuroblastoma. Semin Pediatr Surg. 2012;21(1):2-14. doi: 10.1053/j.sempedsurg.2011.10.009.

Desmoplastic small round cell tumors (DSRCT) diagnosis. Memorial Sloan Kettering Cancer Center website. https://www.mskcc.org/pediatrics/cancer-care/types/desmoplastic-small-round-cell-tumors/diagnosis. Accessed November 11, 2018.

Diffuse intrinsic pontine glioma (DIPG). Dana-Farber Boston Children’s Cancer and Blood Disorders Center website. http://www.danafarberbostonchildrens.org/conditions/brain-tumor/diffuse-pontine-glioma.aspx. Accessed May 29, 2019.

Dobrenkov K, Cheung N-K. GD2-targeted immunotherapy and radioimmunotherapy.  Semin Oncol. 2014;41(5):589-612. doi: 1053/j.seminoncol.2014.07.003.

Ha J-H, Kim J-E, Kim Y-S. Immunoglobulin Fc heterodimer platform technology: from design to applications in therapeutic antibodies and proteins. Front Immunol. 2016;7:394. doi: 10.3389/fimmu.2016.00394.

Hashimoto Y, Penas-Prado M, Zhou S, et al. Rethinking medulloblastoma from a targeted therapeutics perspective. J Neurooncol. 2018;139(3):713-720. doi: 10.1007/s11060-018-2917-2.

Hoseini SS, Guo H, Wu Z, Hatano MN, Cheung N-K. A potent tetravalent T-cell–engaging bispecific antibody against CD33 in acute myeloid leukemia. Blood Advances. 2018;2(11):1250-1258. doi: 10.1182/bloodadvances.2017014373.

Kramer K, Kushner B, Heller G, Cheung N-K. Neuroblastoma metastatic to the central nervous system: the Memorial Sloan-Kettering Cancer Center experience and a literature review. Cancer. 2001;91(8):1510-1519. doi: 10.1002/1097-0142(20010415)91:8<1510::AID-CNCR1159>3.0.CO;2-1.

Kramer K, Kushner BH, Modak S, et al. Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma. J Neurooncol. 2010;97(3):409-418. doi: 10.1007/s11060-009-0038-7.

Larson SM, Carrasquillo JA, Cheung N-K, Press O. Radioimmunotherapy of human tumors. Nat Rev Cancer. 2015;15(6):347-360. doi: 10/1038/nrc3925.

Luther N, Zhou Z, Zanzonico P, et al. The potential of theragnostic 124I-8H9 convection-enhanced delivery in diffuse intrinsic pontine glioma. Neuro Oncol. 2014;16(6):800-806. doi: 10.1093/neuonc/not298.

Medulloblastoma. National Cancer Institute Center for Cancer Research website. https://www.cancer.gov/nci/rare-brain-spine-tumor/tumors/medulloblastoma. Accessed May 7, 2019.

Naxitamab for high-risk neuroblastoma patients with primary refractory disease or incomplete response to salvage treatment in bone and/or bone marrow. Clinicaltrials.gov website (U.S. National Library of Medicine). https://clinicaltrials.gov/ct2/show/NCT03363373. Last updated June 18, 2019. Accessed June 18, 2019.

Nayar G, Ejikeme T, Chongsathidkiet P, et al. Leptomeningeal disease: current diagnostic and therapeutic strategies. Oncotarget. 2017;8(42):73312–73328. doi: 10.18632/oncotarget.20272.

Neuroblastoma. St. Jude Children’s Research Hospital website. https://www.stjude.org/disease/neuroblastoma.html. Accessed July 1, 2019.

Osteosarcoma – childhood and adolescence: symptoms and signs. Cancer.Net website. http://www.cancer.net/cancer-types/osteosarcoma-childhood-and-adolescence/symptoms-and-signs. Accessed May 29, 2019.

Stallard J. Drug delivery approach shows promise for treating a deadly brain tumor in children. Memorial Sloan Kettering Cancer Center website. https://www.mskcc.org/blog/drug-delivery-approach-shows-promise-treating-deadly-brain-tumor-children. June 2018. Accessed May 29, 2019.

Thomas R, Rajeswaran G, Thway K, Benson C, Shahabuddin K, Moskovic E. Desmoplastic small round cell tumour: the radiological, pathological and clinical features. Insights Imaging. 2013;4(1):111-118. doi: 10.1007/s13244-012-0212-x.

Types of cancer treatment. National Cancer Institute (NIH) website. https://www.cancer.gov/about-cancer/treatment/types/. Accessed May 29, 2019.

Wong HH, Hatcher HM, Benson C, et al. Desmoplastic small round cell tumour: characteristics and prognostic factors of 41 patients and review of the literature. Clin Sarcoma Res. 2013;3:14. doi: 10.1186/2045-3329-3-14.

Xu H, Cheng M, Guo H, Chen Y, Huse M, Cheung N-K. Retargeting T cells to GD2 pentasaccharide on human tumors using bispecific humanized antibody. Cancer Immunol Res. 2015;3(3):266-277. doi: 10.1158/2326-6066.CIR-14-0230-T.